Some of you pick things like the Barret .50... don't you think investing in such an "exotic" weapons system might be a poor idea?
It's not like you can sneak into the local Sheels Sporting Goods (or Walmart) after the zombies come and steal yourself some .50 cal. when you run low.
If you're into sniping, maybe something in a .308? Ammo is pretty common. If you go old school and think deer hunting, a .30-30 lever action with scope would work. My mom had a Marlin lever action rifle that was real nice. Shot like a .22 and had almost no recoil.
Desert Eagle... 8 rounds of .50 (or .357 or .44). Plus it weighs a ton. Not for me thanks.

.40 S&W or a double stack 1911 variant. Maybe even a Glock. Smaller, lighter weight, high ammo capacity.
Remember, all you have to do is shoot 'em in the head. Of course, if you miss a perfect head shot... that's where the high ammo capacity comes in.
For armor, I was thinking something like a leather motorcycle suit wth the built in armor. Add a strong pair of high top, thick leather boots so you don't get bit on the ankle. Armored full finger leather gloves that extend over the wrists (again, keeping skin hidden).
Finally, a helmet of some sort. If you went with a motorcycle helm that would work with mods to increase hearing and possibly vision.
Since all it takes is a single bite on the arm to get infected, long sleeves are a must. Hopefully you don't live in Atlanta though. Full leather suit/jacket in the summer? It's like wearing an oven.
Russ
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